Best Protocols for Gut Repair


I recently had the amazing opportunity to interview Kiran Krishnan, Microbiologist. Kiran is an exceptional resource for understanding your digestive woes and his company’s products are my all-time favorites.

In this interview, Kiran dishes out specific protocols you can use to address a variety of conditions.

This interview is for you if you struggle with:

  • Candida overgrowth

  • SIBO (Small Intestinal Bacterial Overgrowth)

  • Food sensitivities

  • Stomachaches

  • Bloating and gas

  • Constipation/diarrhea

  • Or other digestive issues

Watch the video above to get an insider’s view on how to use these protocols for specific digestive issues.

Basic Outline of the Protocol

A general outline of the basic gut protocol is:

A. Treat the gut dysbiosis first:

  1. Basic protocol 2-4 MegaSporeBiotic a day (titrate up slowly!).

  2. If you suspect or know you’ll have die off, titrate up to 4 /day of Mega IgG 2000. I love this product and would really suggest adding it along with the Megasporebiotic.

  3. If you are treating some overgrown unfriendly bacteria, he recommends: 2 capsules each of MegaSporeBiotic, HU58 and RestorFlora spread out in 3 doses a day- 2 of one in AM, 2 of another at lunch, 2 of another in PM. (These are now all in our shop.)

  4. If you have Candida overgrowth, you can add MegaMycoBalance here, working up to 5 twice a day. (This is back in stock at our shop.)

B. If you are doing well for 5-6 weeks on the Megasporebiotic or above protocol, add the MegaPreBiotic at ½ -1 scoop/day in water over the course of the day. (You can discontinue the HU58 and RestoreFlora after 4-6 weeks. You can optionally discontinue the Mega IGG 2000, or you can keep taking it if it’s been helpful for you.)

C. If you are still doing well on step 2 for 3-4 weeks, add in the MegaMucosa, 1 scoop in water/day

After doing step 3 for one month,  you are usually done, but you can stay on 2 MegaSporeBiotic per day if you like, or just use certain products as needed if your tummy is feeling off.

Ideas for Children

Since dosage is based on size, you will generally need to decrease the dosage for children. (For example, if you child is the size of an adult, a full dose will likely be fine, but if your child is half the size of an adult, you will want to work up to half doses.) Some times all it takes is 1/4 or 1/2 of the dose, so you may need to open up the capsules to split up the dose. You can easily mix the powder into smoothies or applesauce.

Notes from our Talk

  • 1:03- How to choose which gut supplements are best for your case

  • 1:52- The root cause of digestive issues: poor microbiome in the gut

  • 6:45- The foundational supplement for digestive issues: a good probiotic (MegaSporeBiotic)

  • 7:09- Best protocol if your digestion is very sensitive or you have a hard time tolerating a lot of foods

  • 12:08 - Best protocol for bloating, reactions to a food you ate, or detox reactions

  • 15:38- Instructions for starting any of Kiran's gut supplements (start with a low dose and work up)

  • 16:40- How to order these supplements internationally

  • 18:30- Using these supplements for neuroinflammation

  • 20:19- The correct order to use the Microbiome Labs products for most cases (MegaSporeBiotic, Mega IgG 200, Prebiotic)

  • 24:29- Protocol for Candida overgrowth (adding MegaMycoBalance in the beginning)

  • 25:19- Protocol for SIBO or known pathogenic overgrowth (adding Using HU58 and RestoreFlora)

  • 28:28- Step one of all gut protocols is dealing with gut dysbiosis in an intelligent way

  • 33:05- Why glutamine is not in MegaMucosa

  • 35:39- New product, MegaGuard, coming out for H. Pylori and dyspepsia and other stomach issues (We now have this in the shop)

  • 37:18- New omega product with updated science to lower inflammation effectively in the gut (MegaOmegas, coming out in September 2019)

  • 40:35- Why leaky gut is the leading cause of vagal dysfunction

  • 44:00- How to find these products

Find Kiran’s Supplements

Find many of his supplements in my shop here.

I am so grateful for you for being a part of my community of detox warriors!

About Kiran Krishnan

Kiran Krishnan is the creator of MegaSporeBiotic and a co-founder of Microbiome Labs. He has over 20 years experience in the probiotics industry and a long background in microbiology and biochemistry. He draws on this background to develop ground-breaking strategies to heal your gut. We are so proud to be online partners with Microbiome Labs!

Do you struggle with digestive issues? Have you ever tried the Microbiome Labs protocols? Share with us in the comments below!


Bridgit Danner, LAc, FDNP, is trained in functional health coaching and has worked with thousands of women over her career since 2004. She is the founder of Women’s Wellness Collaborative llc and

Check our her easy 5-Day DIY Detox Guide here!