Four Manifestations of MCAS
Mast Cell Activation Syndrome (MCAS) is a condition in which mast cells—specialized immune cells —release inflammatory chemicals too easily or too often.
Mast cells normally use histamine to increase blood flow, alert the nervous system, and mobilize defense when a threat is present.
In MCAS, this release happens in response to non-dangerous stimuli like foods, smells, stress, or temperature changes, often because the system has been sensitized by infection, toxicity, trauma or chronic stress.
The result is widespread symptoms because the body’s threat-response system is stuck in over-protection mode.
In this article, I’ll share what MCAS can look like in different phases of illness.
MCAS Type 1: Overstimulated
Looks like:
Reacts to “everything” (not just foods)
Racing heart
Probable POTS
Wired
Fearful
Sensory overwhelm
Dehydration
Emotional fragility
Needs: Gentle supplements in this stage, nervous system calming, do not drain or detox
MCAS Type 2: Reactive
Looks like:
Reacts to foods, chemicals & attempts to detox
Mold rage
Brain fog
Headaches
Toxic ‘flare-ups’
Possible bloating and constipation
Needs: Drainage and organ support
MCAS Type 3: Freeze/Fawn State
Looks like:
Unengaged
Empathic
Poor boundaries
Trauma history
Disassociated
Easily stressed
Gives up easily
Needs: Gentle boundary repair and reconnection to self, decreasing neuroinflammation, return to safety
MCAS Type 4: Depleted
Looks like:
Blood sugar drops
Fatigue
Low blood pressure
Stress intolerance
Hormone dysregulation
Needs: Rebuilding tissue and hormones
Do You See Yourself in These Types?
I’d love to hear it in the comments! Did I miss a type?
I’d say I see type 2 the most, and type 4 is where people will end up if chronic illness goes on too long.
And it’s possibly you will visit all 4 stages.
General Suggestions
MCAS also involves overstimulation, so it’s good to reduce inputs and promote calm with your habits.
Minimize exposure to wifi and cellphone
Minimize exposure to news and notifications (cell phone alerts)
Minimize exposure to irritating foods, scents and environments until more stable
Spend time in nature and with loved ones
Participate in gentle exercise like walking
Meditate twice a day for 10 minutes (Insight Timer is a helpful app, can start with just 1 min twice a day and increase over time)
Learning More
I have a lot of ways you can learn more!